Roflumilast attenuates allergen-induced inflammation in mild asthmatic subjects
نویسندگان
چکیده
منابع مشابه
Roflumilast attenuates allergen-induced inflammation in mild asthmatic subjects
BACKGROUND Phosphodiesterase 4 (PDE4) inhibitors increase intracellular cyclic adenosine monophosphate (cAMP), leading to regulation of inflammatory cell functions. Roflumilast is a potent and targeted PDE4 inhibitor. The objective of this study was to evaluate the effects of roflumilast on bronchoconstriction, airway hyperresponsiveness (AHR), and airway inflammation in mild asthmatic patients...
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ژورنال
عنوان ژورنال: Respiratory Research
سال: 2011
ISSN: 1465-993X
DOI: 10.1186/1465-9921-12-140